Miss Ren, 18, was hospitalized for stiff skin and atrophia as well as dark color on her skullcap and around her right front forehead like a band for more than two years. She was diagnosed that her skullcap was pitted due to skin atrophy, about 3×3cm big and 1cm deep; her vertex on the right side appeared stiff and thick skin, pitted, atrophy and dark color, about 10×2.5cm big. The affected region extended down to the eyebrows, suffering from hypotrichosis and partial lose of right eyebrow, but no flush, itching, pain or high skin temperature. After being treated with Chinese herbal medicinal broths and Yingpiling No.2 as well as bone-marrow stem cell transplantation once every other week for three courses, her skin became plumper than before at the right front forehead and the hair of the right eyebrow grew more.