The transplantation therapy of stem cells is to take a given amount of bone marrow from a patient in vivo, and then separate the stem cells in a laboratory to prepare them into autologous bone-marrow stem cells injection, and eventually inject back into the affected region of the patient.

The transplantation therapy of autologous bone-marrow stem cells is able to treat localized scleroderm effectively due to the following reasons. Firstly, the bone marrow stem cells have function of differentiation, which means they can be differentiated into histiocytes needed by organism at the transplanted region so as to repair the damaged tissues. Secondly, the bone marrow stem cells may differentiate and proliferate at the transplanted region to generate active substances like enzymes and special peptides that can stimulate organismic tissues to grow so as to quicken tissue regeneration. Thirdly, the bone marrow stem cells are able to induce and enhance the tolerance of local immunity so as to inhibit further progress of localized scleroderm and skin lesion. Finally, the bone marrow stem cells may urge proliferation of local capillary, correct the undernutrition of the tissues around the region affected, which is favorable in restoring the pathogenic skin and subcutaneous tissues of scleroderma sufferers, thus to regain the normal function of skin.

The transplantation therapy of autologous stem cells is suitable for the skin diseases dominated by atrophia because of stem cells' differentiation and proliferation, especially for atrophia limited in a small region. In addition, this therapy is worthwhile for treatment of macular atrophy, progressive idiopathic atrophoderma, facial hemiatrophy and atrophia of subcutaneous fat caused by local injection when other therapies show not good effects. Generally speaking, a course of treatment with this therapy is required to inject at the local region affected three or four times at interval of two or three weeks. The transplantation therapy of autologous stem cells is still a means of expectant treatment though it has certain efficacy, which however cannot terminate the recurrence and progress of disease by the root. A normal treatment combining TCM treatment with other supplementary treatments is still needed.

Tongluo Runfu Soothing Cream is made up with pure herbs as per a prescription worked out on the basis of differentiation of symptoms and signs under the TCM principle that the therapy for internal disease can also be used in external treatment. It is produced with advanced pharmaceutical technology into compound medical ointment, which can be directly acted on skin and joints to rectify skin swelling, sclerosis, atrophia, pigmentation, depigmentation, arthrodynia, contracture and Reynauds syndrome. In clinical practice, this herbal compound medical ointment is proven easy for application and definite effect.