Ms.Jiang, 52, was hospitalized for suffering from stiff skin with limbs for six years and limb ulcer for two years. His symptoms were as follows when came to our hospital: stiff skin all over along with pigmentation, atrophy as well as pale skin and lose of pigments obviously, cyanosis of both hands at cold temperature, ulcer and pain with the finger joints, not smooth movement with hand joints. She was diagnosed as systemic scleroderma and treated with Chinese medicinal broths to warm yang and activate the channels, oral administration of No.9 Yingpiling, intravenous transfusion of Jiweiling Injection and Ligustrazine Injection plus Chinese herbal ointment applied to the ulcerous regions in addition to keeping the limbs warm. After one week's treatment, the sensation of pain in the ulcerous regions was relieved and dried obviously while granulation tissue could be seen growing. Twenty days later, the ulcer healed basically and the joints became smooth when moving than before.